Perspectives

Perspectives

Research, insights, and news from Outpost Bio.

Blog

Can Microbiome Foundation Models Transfer Across Biomes?

Can Microbiome Foundation Models Transfer Across Biomes?

Microbial communities are everywhere: in the human gut, on skin, in soil, in oceans, in wastewater systems, and in engineered bioreactors. These environments look very different biologically, and the datasets we have for them are uneven. Some biomes are deeply represented in public repositories. Others remain sparse, fragmented, or hard to measure at scale.

Microbial communities are everywhere: in the human gut, on skin, in soil, in oceans, in wastewater systems, and in engineered bioreactors. These environments look very different biologically, and the datasets we have for them are uneven. Some biomes are deeply represented in public repositories. Others remain sparse, fragmented, or hard to measure at scale.

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Podcasts
Research
News
Blog
Blog
Can Microbiome Foundation Models Transfer Across Biomes?

Microbial communities are everywhere: in the human gut, on skin, in soil, in oceans, in wastewater systems, and in engineered bioreactors. These environments look very different biologically, and the datasets we have for them are uneven. Some biomes are deeply represented in public repositories. Others remain sparse, fragmented, or hard to measure at scale.

Blog
For the Poop-Curious

Have you ever wondered how people collect stool samples for microbiome research? No? Consider yourself lucky and normal 😉.

News
An AI-Powered Approach Decodes Gut Microbiome Interactions

Outpost Bio leverages machine learning to develop models that can identify interactions among stool microbes to improve drug development. Written by Shelby Bradford, PhD and published in The Scientist.

Podcast
How AI is Unlocking the Human Microbiome

Blog
Why We're Open Sourcing Our First Model

Today's a big one for us! We're releasing our first model at Outpost, and we're open-sourcing it.  I want to talk about the why before the what, because this was a values call for us. And I think it says a lot about the kind of company we're building.

Podcast
From Models to Medicine: The Microbiome is Messier Than You Think

Jenny Yang is the co-founder and CEO of Outpost Bio, where her team is working to make human microbiology computable. In this episode, she breaks down why bias in ML models is so easy to miss. High overall accuracy can hide terrible performance on specific subgroups, and in healthcare, that gap has consequences. She traces the problem upstream, from skewed training datasets to the way clinical definitions themselves carry historical bias, and explains the real trade-offs involved in trying to correct for it.

Podcast
Turning Poop to Gold: Jenny Yang, Outpost Bio

Jenny Yang's Live Interview on Ventures- Discussing how the poop science, AI, and the $3.5M pre-seed leading to Outpost's success.

Podcast
Turning Poop to Gold: Jenny Yang, Outpost Bio
News
An AI-Powered Approach Decodes Gut Microbiome Interactions

Outpost Bio leverages machine learning to develop models that can identify interactions among stool microbes to improve drug development. Written by Shelby Bradford, PhD and published in The Scientist.

News
An AI-Powered Approach Decodes Gut Microbiome Interactions
Podcast
Beyond the Clinic: Innovation in Healthcare

Dr. Jenny Yang, CEO and Co-Founder of Outpost Bio, shares how AI is unlocking the microbiome’s potential to transform drug development. From overcoming the biggest barriers in the field to translating insights into real-world impact, Jenny explains the science, strategy, and vision behind Outpost Bio, plus her hot take on where the industry is heading.

Podcast
Beyond the Clinic: Innovation in Healthcare
Blog
Can Microbiome Foundation Models Transfer Across Biomes?

Microbial communities are everywhere: in the human gut, on skin, in soil, in oceans, in wastewater systems, and in engineered bioreactors. These environments look very different biologically, and the datasets we have for them are uneven. Some biomes are deeply represented in public repositories. Others remain sparse, fragmented, or hard to measure at scale.

Blog
Can Microbiome Foundation Models Transfer Across Biomes?
Blog
Can Transformers Learn the Language of the Microbiome?

Drugs that you take interact with a complex microbial ecosystem in your gut. Trillions of microorganisms call the human digestive tract home and interact with one another and with their human host. This microbial world can directly modify drug structure (1–4), influence host immune responses (5,6), and alter pharmacokinetics (4,7). Currently, most drug development programs choose to ignore the gut microbiome because a reliable method to predict how it impacts drugs does not exist.

Blog
Can Transformers Learn the Language of the Microbiome?
News
Exclusive: Inside Outpost Bio ’s $3.5M mission to turn the microbiome into predictive AI infrastructure

Outpost Bio, a deep-tech startup with teams in London and Boston, wants to make human microbiology easier to understand through computation. Their Lab-in-the-Loop platform that fuses machine learning with automated experiments, creating a constant feedback loop between data and discovery.

News
Exclusive: Inside Outpost Bio ’s $3.5M mission to turn the microbiome into predictive AI infrastructure

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